Jamestown was the first permanent British colony in the US and was located not far from Williamsburg. On this page are listed several resources that deal with the history of Jamestown, early works written by settlers, and genealogies of the Jamestown colonists.
Note: This is not a complete list. To locate more, search Swem's catalog by subject for “Jamestown (Va.) history.”
Beyond tracing your ancestors to possibly settling in Jamestown, there is also the Jamestowne Society, an invitation-only group of those who descend from the early settlers at the site. For those seeking membership in the Jamestowne Society, a list of qualifying ancestors is on their website.